![]() Results: For A549 xenografts in radiation alone, gefitinib alone and combination therapy groups, the percentage of tumor growth inhibition was 22.7%, 12.4% and 38.2%, respectively (F=25.75, P=0.000). Percentage of tumor growth inhibition, growth delay time and regrowth delay time were evaluated. Tumor diameter was measured every other day. In the combination group, radiotherapy was performed 2 hours after Gefitinib administration. Gefitinib was daily administered by gavage at 100 mg/(kg Radiation schedule was 3 fractions of 5 Gy, once daily. The mice were derided into 4 groups: control, irradiation alone, Gefinitib alone and radiation combined with Genifitib. Methods: Human lung adenocarcinoma cell line A549 was used to establish nude mouse xenograft tumor model. Objective: To investigate the effect of Gefitinib on radiosensitivity of human lung adenocarcinoma xenograft in nude mouse. Wang Hui Li Tianran Tian Jiahe Qu Baolin Zhu Hui ![]() International Nuclear Information System (INIS) The effect of .Īnti-EGFR therapy radiosensitizes human lung adenocarcinoma xenograft in nude mouse Xenogen in vivo imaging system was used to monitor tumor growth and metastasis. Methods: Withaferin A was injected through a portal vein to the orthotopic liver tumor in a nude mice model. ![]() Purpose: To investigate the effect of withaferin A on tumor growth and metastasis in liver in a nude mouse model. Withaferin A Suppresses Liver Tumor Growth in a Nude Mouse.
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